A Case of Propofol-Induced Delayed-Onset Refractory Myoclonic Seizures

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A Case of Propofol-Induced Delayed-Onset Refractory Myoclonic Seizures

Propofol, a GABA-mediated inhibitor of excitatory neurotransmitter, is a popular intravenous agent for general anesthesia and sedation. Its side effects reportedly include opisthotonus, seizures, and myoclonus, and are usually manageable. We present a patient who developed propofol-induced delayed-onset refractory myoclonic seizures that resisted antiepileptic drugs.

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Propofol-related myoclonic seizures

Propofol is a popular agent for induction and maintenance of anaesthesia, as well as an excellent sedative agent widely used in ambulatory anaesthesia. Although involuntary movements due to propofol are well known, the occurrence of propofol-related seizure activity in patients with no previous history of epilepsy is less well highlighted. These seizures may occur at all stages of anaesthesia: ...

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Refractory Seizures in Tramadol Poisoning: A Case Report

Background: Tramadol, an analgesic drug abused by opioid addicts, is also abused accidentally or for suicidal purposes. Tramadol poisoning can induce CNS depression, seizures, coma, and ultimately death. Case: In this report, a 30-year-old male was admitted to the emergency department due to suicidal attempt with ingestion of 14000 mg (140 tablet 100 mg) of tramadol. He had history of suicidal...

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Treatment of refractory seizures in eclampsia with propofol: A case report

Propofol, which is a unique non-barbiturate anaesthetic agent, has been used in nearly 33 studies in RSE with good results. However the proor anticonvulsant effects of propofol remain a matter of controversy, with many reports descr ibing abnormal movements, postur ing and seizure-like activity with its use. On the other hand, systematic studies in both humans and animals strongly suggest that ...

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Focal-onset myoclonic seizures and secondary bilateral synchrony.

We present a child with myoclonic seizures, epileptic spasms and generalized epileptiform discharges on scalp EEG. Magnetoencephalography and coherence-phase analysis for scalp EEG suggested focal onset in the left hemisphere. Intracranial video EEG confirmed seizure onset in the left frontal lobe with ictal high-frequency oscillations. Left frontal lobectomy suppressed his seizures. Subsets of...

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ژورنال

عنوان ژورنال: Journal of Clinical Neurology

سال: 2007

ISSN: 1738-6586

DOI: 10.3988/jcn.2007.3.3.154